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PubMed COVID-19 Clinical Care

1471 - 1480 of 4912 results found

A Brief Focus on SARS-CoV-2 Genomic Evolution and Vaccines

Date
Friday, October 27, 2023 - 4:00 AM
Description
Severe acute respiratory syndrome-coronavirus type 2 (SARS-CoV-2) emerged in a live animal market in the Hubei Province of Wuhan in China in late 2019 and was declared a pandemic by the World Health Organization (WHO) on 11 March 2020 [...].

An Update on the Current State of SARS-CoV-2 Mac1 Inhibitors

Date
Friday, October 27, 2023 - 4:00 AM
Description
Non-structural protein 3 (nsp3) from all coronaviruses (CoVs) contains a conserved macrodomain, known as Mac1, that has been proposed as a potential therapeutic target for CoVs due to its critical role in viral pathogenesis. Mac1 is an ADP-ribose