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PubMed COVID-19 Clinical Care

31931 - 31940 of 42847 results found

Common Coagulopathies Associated With COVID-19 Patients

Date
Friday, May 26, 2023 - 4:00 AM
Description
The coronavirus disease 2019 (COVID-19) outbreak, which first appeared in the Chinese province of Hubei city of Wuhan, has been spreading internationally since December 2019. The World Health Organization (WHO) declared the coronavirus illness from

Protocol for production and purification of SARS-CoV-2 3CLpro

Date
Friday, May 26, 2023 - 4:00 AM
Description
3CL^(pro) protease from SARS-CoV-2 is a primary target for COVID-19 antiviral drug development. Here, we present a protocol for 3CL^(pro) production in Escherichia coli. We describe steps to purify 3CL^(pro), expressed as a fusion with the